Each monthly open access (subscription-free), online issue of The Lancet Global Health features original research, commentary, and correspondence, and our content is complemented by regular blog posts. Our focus is on disadvantaged populations, be they whole economic regions or marginalised groups within otherwise prosperous nations, with a preference for the following topics: reproductive, maternal, neonatal, child, and adolescent health; infectious diseases, including neglected tropical diseases; non-communicable diseases; mental health; the global health workforce; health systems; surgery; and health policy.