Revista Clínica Espaola published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI).The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Espaola is subject to a thorough double blind review of the received articles written in Spanish or English. Nine issues are published each year, including mostly originals, reviews and consensus documents.